Yazar "Coşkun, Zeynep Mine" için listeleme
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Biochemical and morphologic changes by sitagliptin in diabetic rat liver
Background: The aim of this study was to determine the effects of sitagliptin treatment on type-2 diabetic liver tissue. -
Cytotoxic, anti-proliferative and anti-microbial activities of extract from cladonia pocillum
Coşkun, Zeynep Mine; Ersöz, Melike; Açıkgöz, Birkan; Karaltı, İskender; Çobanoğlu, Gülşah; Sesal, Cenk (2014)Lichens produce a wide variety of seconder metabolites which have a potential use as anti-microbial, cytotoxic, fungitoxic, anti-feedant, anti-oxidant, anti-inflammatory [1-3]. Many studies report that, the efficacy of ... -
Diyabetik sıçanlara Δ9-tetrahidrokannabinol uygulanmasının serum lipidleri, insulin ve glukagon peptidleri üzerindeki etkileri
Coşkun, Zeynep Mine; Bolkent, Sema (Türk Biyokimya Derneği, 2012)Diabetes mellitus insuline bağımlı olmayan, insulin direnci ile karakterize kronik bir hastalıktır. Diabetes mellitus’da genellikle hiperglisemi ile birlikte hiperlipidemi de gelişir. Cannabis sativa’nın ana psikoaktif ... -
The Effects of Camellia sinensis Extract on Proliferation, Apoptosis and Oxidative Stress in Insulinoma INS-1 Cells
Objective: Green tea (Camellia sinensis) is one of the most consumed beverages in the world. C. sinensis consumption may prevent tumor and other diseases. Insulinomas are pancreatic islet cell tumors. In present study, the ... -
Embryological and cytochemical features of Scilla autumnalis L.
Coşkun, Zeynep Mine; Ünal, Meral (TUBİTAK, 2010)Nucellar epidermal cells in the micropylar region of Scilla autumnalis L. differentiate into a nucellar cap. It secretes a PAS-positive exudate filling the micropyle. A group of cells at the chalazal end of the nucellus ... -
Evaluation of oxidative stress markers in type-2 diabetic rat kidney with treated Δ9-THC
Oxidative stress plays a major role in the pathogenesis of diabetes mellitus. Impaired redox homeostasis can lead to the damage of macromolecules and insulin resistance. Thus, oxidative stress promotes the development of ... -
Evaluation of Δ(9)-tetrahydrocannabinol metabolites and oxidative stress in type 2 diabetic rats.
Coşkun, Zeynep Mine; Bolkent, Sema (Mashhad University of Medical Sciences, 2016)Objectives: The object of the study is to examine the effects of Δ9-tetrahydrocannabinol (THC) against oxidative stress in the blood and excretion of THC metabolites in urine of type 2 diabetic rats. Materials and Methods: ... -
Oxidative stress and cannabinoid receptor expression in type-2 diabetic rat pancreas following treatment with Δ9-THC
Coşkun, Zeynep Mine; Bolkent, Sema (Wiley Pub., 2014)The objectives of study were (a) to determine alteration of feeding, glucose level and oxidative stress and (b) to investigate expression and localization of cannabinoid receptors in type-2 diabetic rat pancreas treated ... -
Regulation of oxidative stress and somatostatin, cholecystokinin, apelin gene expressions by ghrelin in stomach of newborn diabetic rats
Coşkun, Zeynep Mine; Saçan, Özlem; Karatuğ, Ayşe; Türk, Neslihan; Yanardağ, Refiye; Bolkent, Şehnaz; Bolkent, Sema (Elsevier, 2013)The aim of the study was to determine whether ghrelin treatment has a protective effect on gene expression and biochemical changes in the stomach of newborn streptozotocin (STZ) induced diabetic rats. In this study, four ... -
Screening of anti-oxidative effects in Camellia sinensis L. leaves treated with boric acid
İsmailoğlu, Işıl; Coşkun, Zeynep Mine; Ersöz, Melike; Turan, Murat Ali (Society of Cell Membranes and Free Oxygen Radicals, 2014)Camellia sinensis L. (tea) is one of the most widely consumed drink in the World. The anti-oxidant role of boric acid has been reported. The present study was aimed to evaluate the alteration of anti-oxidative effects of ... -
Screening of antimicrobial activity and cytotoxic effects of two Cladonia species.
Açıkgöz, Birkan; Karaltı, İskender; Ersöz, Melike; Coşkun, Zeynep Mine; Çobanoğlu, Gülşah; Sesal, Cenk (De Gruyter, 2013)The present study explores the antimicrobial activity and cytotoxic effects in culture assays of two fruticose soil lichens, Cladonia rangiformis Hoffm. and Cladonia convoluta (Lamkey) Cout., to contribute to possible ... -
The role of Δ9-Thc on oxidative stress status of brain and cerebellum in type-2 diabetes
Bolkent, Sema; Coşkun, Zeynep Mine (Society of Cell Membranes and Free Oxygen Radicals, 2014)Diabetes Mellitus is a metabolic disorder characterized by hyperglycemia. The hyperglycemia leads to neuronal damage [1]. The development and progression of diabetes mellitus and its complications are derived from increased ... -
Vascular responses disrupted by fructose-induced hyperinsulinemia improved with delta-9- tetrahydrocannabinol
Todurga Seven, Zeynep Gizem; Gokdemir, Selim; Özyazgan, Sibel; Köse, Çağla; Coşkun, Zeynep Mine; Akkan, A. Gökhan; Bolkent, Sema (2021)Objectives: In recent years, cannabinoids have been shown to have beneficial effects on diabetic vascular complications. Vascular complications due to fructose-induced hyperinsulinemia (HI) and diabetic vascular complications ...